Bright Earth foods

optin graphic
"Let food be thy medicine. Let medicine be thy food." ~ Hippocrates
free delivery icon Free Delivery On All Orders Over $100

Algae

Algae as Key Immune System Supporter

Woman with ColdComplex polysaccharides present in wild blue green algae contribute to the activation Natural Killer (NK) cells, the human body’s primary immune defense mechanism. These cells travel in the blood stream in a state of rest, but can be immediately recruited into tissues by chemical signals and activated through various mechanisms to kill virus-infected and cancer cells, b) divide and make more NK cells, and c) secrete substances that attract other cells into the site. Research on the polysaccharides in DLT’s Aphanizomenon flos aquae provides strong support of activation of NK cells in laboratory tests and supports immune surveillance of NK cells in the body.

In Vitro Testing

In vitro testing confirmed the inflammation modulation and antioxidant properties of AFAninPlusTM (Hart et al 2007). 1. AFAninPlusTM contains Phycocyanin, known to inhibit the enzymatic activity of cyclooxygenase-2 (COX 2) involved in the inflammation cascade. 2. Antioxidants in AFAninPlusTM are able to enter into and protect the lipid bilayer cell membrane and protect living cells from intracellular oxidative stress. 3. AFAninPlusTM activated NK cell expression of CD69, a marker compound that indicates increased scavenging and killing of virus containing or cancerous cells.

Clinical Study on Visual Acuity and Cognitive Function

In vivo testing confirmed consumption of Aphanizomenon flos-aquae (Jensen et al 2000): 1. Significantly improved reaction time and ability to multitask according to multi-sensory input. 2. Significantly improved visual acuity as measured by the reduction in size of the Physiological Blind Spot (PBS), when compared to placebo. 3. Showed a rapid improvement in visual acuity (within 2-10 minutes). 4. Showed a prolonged result, still effective at 1 hour after consumption.

Mechanisms of action involved in the rapid improvement are attributed in part to the PEA content of Aphanizomenon flos-aquae. Additional testing showed at least part of the effect of Aphanizomenon flos-aquae on cognitive function was due to rapid oral uptake of psychoactive compounds, such as PEA.

References:

Berthold-Losleben M, Heitmann S, Himmerich H. Anti-inflammatory drugs in psychiatry. (2009). Inflammation and Allergy-Drug Targets, Sep; 8(4):266-76.

Dhabhar FS, Burke HM, Epel ES, Mellon SH, Rosser R, Reus VI, Wolkowitz OM. (2009). Low serum IL-10 concentrations and loss of regulatory association between IL-6 and IL-10 in adults with major depression. Journal of Psychiatric Research, Jul; 43(11):962-9.

Hart AN, Zaske LAM, Patterson KM, Drapeau C, Jensen GS. (2007). Natural killer cell activation and modulation of chemokine receptor profile in vitro by an extract from the cyanophyta Aphanizomenon flos-aquae. Journal of Medicinal Food, 10(3): 435-441.

Jensen GS, Ginsberg DI, Huerta P, Citton M, Drapeau C (2000). Consumption of Aphanizomenon flos aquae has rapid effects on the circulation and function of immune cells in humans. A novel approach to nutritional mobilization of the immune system. JANA, vol. 2 (3):50-58.

Jensen, GS, Carter SG, Redman KA, Benson KF, Ehmann A, Guthrie J, Turner J, Drapeau C. Cognitive enhancement and immune modulating properties of an antioxidant-rich microalgae extract, AFAninPlusTM. SSW09 poster session.

Kim YK, Lee SW, Kim SH, Shim SH, Han SW, Choi SH, Lee BH. (2008). Differences in cytokines between non-suicidal patients and suicidal patients in major depression. Progress in Neuropsychopharmacol Biological Psychiatry, Feb 15; 32(2):356-61.

Reddy CM, Bhat VB, Kiranmai G, Reddy MN, Reddanna P, Madyastha K. (2000). Inhibition of cyclooxygenase-2 by C-phycocyanin, a biliprotein from Spirulina platensis. Biochemical and Biophysical Research Communications, 277(3):599-603.

Sabelli HC, Fawcett J, Gusovsky F, Javaid JI, Wynn P, Edwards J, Jeffriess H, Kravitz H. (1986). Clinical studies on the phenylethylamine hypothesis of affective disorder: urine and blood phenylacetic acid and phenylalanine dietary supplements. Journal of Clinical Psychiatry, 47(2):66-70.

Sabelli HC, Fink P, Fawcett J, Tom C. (1996). Sustained antidepressant effect of PEA replacement. Journal of Neuropsychiatry and Clinical Neurosciences, 8(2):168-71.

Vadiraja B, Bhat V, Madaystha K. (2000). C-Phycocyanin: A potent peroxyl radical scavenger in vivo and in vitro. Biochemical and Biophysical Research Communications, 275, 20-25.

Tagged

Leave a reply

Your email address will not be published. Required fields are marked *

*